Is Anticancer Drug Development Heading in the Right Direction?

Is anticancer drug development heading in the right direction?

The success of molecularly targeted agents, such as imatinib, has led to expectations of a new era in anticancer drug development, and to a greatly increased focus on targeting as a strategy. However, the number of successes to date is small, and recent results suggest that the success of imatinib, for instance, in treating chronic myelogenous leukemia and gastrointestinal stromal tumor may be ...

Heading in the Right Direction

Stochastic topological models, and hidden Markov models in particular, are a useful tool for robotic navigation and planning. In previous work we have shown how weak odometric data can be used to improve learning topological models, overcoming the common problems of the standard Baum-Welch algorithm. Odometric data typically contain directional information, which imposes two difficulties: First...

Is the HCV pipeline heading in the right direction?

o t p t f t l d b t 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 Hepatitis C (HCV) is a global health concern, with 180 million people infected worldwide. Advances n HCV therapy do not necessarily result in improvement f patient outcomes unless specific patient needs and herapeutic options a...

Are You Heading in the Right Direction?

Are we heading in the right direction?

T Indian Society of Periodontology (ISP) is one of the fastest growing dental specialty societies in India and has even had the distinction of being one of the highest tax paying one last year. Since its inception in the mid-seventies the ISP has grown with leaps and bounds, witnessing an exponential rise in membership strength over the last decade. This has coincided with the start of post-gra...